I read through the syllabus in order to understand the final essay. The first word came to my mind is a controversial topic. It’s interesting to think of controversial topics related to the microbiome. My first thought is microbiome species, similar to biological species when I searched the definition of microbiome at beginning of the class. I found that this controversial topic brought researchers different areas and classifications for microbiome species concept (MSC). Another topic is the relationship between microbiome and disease. Researchers have been studying whether the variant microbiome are from responses of human to environmental factors or through heriterity. The variant microbiome caused disease related to immune responses in beginning to cancer period, local microenvironment, or potential inflammations. Also, the topic about the role of Helicobacter pylori in the pathogenesis of gastric reflux esophagus disease (GERD). I’m curious why eradication of H.pylori doesn’t induce in these disorders, and whether or not, antibiotic treatments work perfectly for these diseases. The “ commensalisms” suggested that eradication the H.pylori causes the worse GERD and asthma. However, H.pylori infection can lead to gastric cancer. So whether or not we should kill all H.pylori or just restrict their growth in symptomatic or nonsymptomatic individuals.
I have three topics including classification of the microbiome, the role of the microbiome in disease, and eradication of H.pylori in symptomatic or nonsymptomatic infected people related to GERD. I try to remind myself about classifications about microbiome, but I don’t have a lot of ideas about this topic. So, I start to consider about the classification of microbiome and H.pylori. Also, the variant microbiome is a new topic to me. I read the information about microbiome which is a combination of genetic material and influences of environmental factors. But How microbiome change? What trigger their changes? Besides, I did my midterms about H.pylori topic, and at that point, I focused on what is H.pylori, how people gets infected, and how treatments work in H.pylori infections. I understood about H.pylori had all negative effects and side effects from H.pylori treatments using antibiotic. However, now I’m going to work on a controversial topic about H.pylori. It sounds cool to debate myself about H.pylori. Maybe, it changes my perspective about H.pylori infections in different ways.
I think that my final essay will cover eradication or preservation of H.pylori. It’s interesting to turn my mind up and down sides about H.pylori. I may start my essay from outlining the organization of my paper such as discovery and characteristics of H.pylori related to how H.pylori affects human health, the idea of eradication of H.pylori (pros/cons), the preservation of H.pylori, and my standing side at the end. I will build my introduction, body paragraph according to ideas above, and conclusion. First, I will read again the articles which I found for my midterm and selected which one I would use for the final. Then I continue to find articles about H.pylori infections, eradication treatments, and preservation of H.pylori. I will underline main findings, howe researchers conducted their studies, and information support for my ideas also. Then I will put the information into my outline. Finally, I will write and build a completely paragraphs.
