Siva Kolluri’s publications (Pubmed)
Koch DC, Jang HS, O’Donnell EF, Punj S, Kopparapu PR, Bisson WH, Kerkvliet NI, Kolluri SK. Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1. Oncogene. 2015 Apr 13 link
Perkins A, Phillips JL, Kerkvliet NI, Tanguay RL, Perdew GH, Kolluri SK, Bisson WH. A structural switch between agonist and antagonist bound conformations for a ligand-optimized model of the human aryl hydrocarbon receptor ligand binding domain. Biology (Basel). 2014 Oct 17;3(4):645-69. link
Gerlach CV, Das SR, Volz DC, Bisson WH, Kolluri SK, Tanguay RL. Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish. Aquat Toxicol. 2014 Sep;154:71-9. link
Punj S, Kopparapu P, Jang HS, Phillips JL, Pennington J, Rohlman D, O’Donnell E, Iversen PL,Kolluri SK, Kerkvliet NI. Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease. PLoS One. 2014 Feb 19;9(2):e88726. link
O’Donnell EF, Koch DC, Bisson WH, Jang HS, Kolluri SK. The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells. Cell Death Dis. 2014 Jan 30;5:e1038. link
O’Donnell EF, Kopparapu PR, Koch DC, Jang HS, Phillips JL, Tanguay RL, Kerkvliet NI, Kolluri SK. The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells. PLoS One. 2012;7(7):e40926. link
Alternate glucocorticoid receptor ligand binding structures influence outcomes in an in vivo tissue regeneration model. Sengupta S, Bisson WH, Mathew LK, Kolluri SK, Tanguay RL. Comp Biochem Physiol C Toxicol Pharmacol. 2012 Aug;156(2):121-9.
Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism. Smith KJ, Murray IA, Tanos R, Tellew J, Boitano AE, Bisson WH, Kolluri SK, Cooke MP, Perdew GH. J Pharmacol Exp Ther. 2011 Jul;338(1):318-27.
Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro. Benninghoff AD, Bisson WH, Koch DC, Ehresman DJ, Kolluri SK, Williams DE. Toxicol Sci. 2011 Mar;120(1):42-58.
Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′,4′-dimethoxy-α-naphthoflavone. Murray IA, Flaveny CA, Chiaro CR, Sharma AK, Tanos RS, Schroeder JC, Amin SG, Bisson WH,Kolluri SK, Perdew GH. Mol Pharmacol. 2011 Mar;79(3):508-19.
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor. O’Donnell EF, Saili KS, Koch DC, Kopparapu PR, Farrer D, Bisson WH, Mathew LK, Sengupta S, Kerkvliet NI, Tanguay RL, Kolluri SK. PLoS One. 2010 Oct 1;5(10). pii: e13128.
NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling. Zhou H, Liu W, Su Y, Wei Z, Liu J, Kolluri SK, Wu H, Cao Y, Chen J, Wu Y, Yan T, Cao X, Gao W, Molotkov A, Jiang F, Li WG, Lin B, Zhang HP, Yu J, Luo SP, Zeng JZ, Duester G, Huang PQ, Zhang XK. Cancer Cell. 2010 Jun 15;17(6):560-73.
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands. Bisson WH, Koch DC, O’Donnell EF, Khalil SM, Kerkvliet NI, Tanguay RL, Abagyan R, Kolluri SK. J Med Chem. 2009 Sep 24;52(18):5635-41.
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer. Kolluri SK, Zhu X, Zhou X, Lin B, Chen Y, Sun K, Tian X, Town J, Cao X, Lin F, Zhai D, Kitada S, Luciano F, O’Donnell E, Cao Y, He F, Lin J, Reed JC, Satterthwait AC, Zhang XK. Cancer Cell. 2008 Oct 7;14(4):285-98.
Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma. Luciano F, Krajewska M, Ortiz-Rubio P, Krajewski S, Zhai D, Faustin B, Bruey JM, Bailly-Maitre B, Lichtenstein A, Kolluri SK, Satterthwait AC, Zhang XK, Reed JC. Blood. 2007 May 1;109(9):3849-55. Erratum in: Blood. 2009 Feb 12;113(7):1613.
Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt. Han YH, Cao X, Lin B, Lin F, Kolluri SK, Stebbins J, Reed JC, Dawson MI, Zhang XK. Oncogene. 2006 May 18;25(21):2974-86.
TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway. Weiss C, Faust D, Dürk H, Kolluri SK, Pelzer A, Schneider S, Dietrich C, Oesch F, Göttlicher M. Oncogene. 2005 Jul 21;24(31):4975-83.
The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis. Kolluri SK, Corr M, James SY, Bernasconi M, Lu D, Liu W, Cottam HB, Leoni LM, Carson DA, Zhang XK. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2525-30.
Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting. Cao X, Liu W, Lin F, Li H, Kolluri SK, Lin B, Han YH, Dawson MI, Zhang XK. Mol Cell Biol. 2004 Nov;24(22):9705-25. Erratum in: Mol Cell Biol. 2005 Jan;25(1):524.
Determinants of retinoid X receptor transcriptional antagonism. Cavasotto CN, Liu G, James SY, Hobbs PD, Peterson VJ, Bhattacharya AA, Kolluri SK, Zhang XK, Leid M, Abagyan R, Liddington RC, Dawson MI. J Med Chem. 2004 Aug 26;47(18):4360-72.
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, Dawson MI, Reed JC, Zhang XK. Cell. 2004 Feb 20;116(4):527-40.
Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells. Kolluri SK, Bruey-Sedano N, Cao X, Lin B, Lin F, Han YH, Dawson MI, Zhang XK. Mol Cell Biol. 2003 Dec;23(23):8651-67.
Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells. James SY, Lin F, Kolluri SK, Dawson MI, Zhang XK. Cancer Res. 2003 Jul 1;63(13):3531-8.
Regulation of retinoic acid-induced inhibition of AP-1 activity by orphan receptor chicken ovalbumin upstream promoter-transcription factor. Lin F, Kolluri SK, Chen GQ, Zhang XK. J Biol Chem. 2002 Jun 14;277(24):21414-22.
Novel target genes of the Ah (dioxin) receptor: transcriptional induction of N-myristoyltransferase 2. Kolluri SK, Balduf C, Hofmann M, Göttlicher M. Cancer Res. 2001 Dec 1;61(23):8534-9.
Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity. Dawson MI, Hobbs PD, Peterson VJ, Leid M, Lange CW, Feng KC, Chen Gq, Gu J, Li H, Kolluri SK, Zhang Xk, Zhang Y, Fontana JA. Cancer Res. 2001 Jun 15;61(12):4723-30.
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Li H, Kolluri SK, Gu J, Dawson MI, Cao X, Hobbs PD, Lin B, Chen G, Lu J, Lin F, Xie Z, Fontana JA, Reed JC, Zhang X. Science. 2000 Aug 18;289(5482):1159-64.
Unique anti-activator protein-1 activity of retinoic acid receptor beta. Lin F, Xiao D, Kolluri SK, Zhang X. Cancer Res. 2000 Jun 15;60(12):3271-80.
Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells. Lin B, Chen GQ, Xiao D, Kolluri SK, Cao X, Su H, Zhang XK. Mol Cell Biol. 2000 Feb;20(3):957-70.
p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells. Kolluri SK, Weiss C, Koff A, Göttlicher M. Genes Dev. 1999 Jul 1;13(13):1742-53.
Mapping of epitopes on porcine zona pellucida-3 alpha by monoclonal antibodies inhibiting oocyte-sperm interaction. Gupta SK, Chadha K, Harris JD, Yurewicz EC, Sacco AG, Kolluri SK, Afzalpurka A. Biol Reprod. 1996 Aug;55(2):410-5.
Weiss C, Kolluri SK, Kiefer F, Göttlicher M. Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor. Exp Cell Res. 1996 Jul 10;226(1):154-63. link
Kolluri SK, Kaul R, Banerjee K, Gupta SK. Nucleotide sequence of cDNA encoding bonnet monkey (Macaca radiata) zona pellucida glycoprotein-ZP3. Reprod Fertil Dev. 1995;7(5):1209-12. link
