{"id":6257,"date":"2016-11-10T17:43:10","date_gmt":"2016-11-11T01:43:10","guid":{"rendered":"http:\/\/blogs.oregonstate.edu\/impact\/?p=6257"},"modified":"2017-03-16T17:43:56","modified_gmt":"2017-03-17T00:43:56","slug":"enhanced-nmr-facility-positions-osu-regional-spectroscopy-center","status":"publish","type":"post","link":"https:\/\/dev.blogs.oregonstate.edu\/impact\/2016\/11\/enhanced-nmr-facility-positions-osu-regional-spectroscopy-center\/","title":{"rendered":"Enhanced NMR Facility positions OSU as regional spectroscopy center"},"content":{"rendered":"

Watch a video<\/a> of the ceremony and keynote address.<\/em><\/p>\n

The College of Science celebrated the new Macromolecular Nuclear Magnetic Resonance instrument (NMR) with a Dedication and Ribbon-Cutting Ceremony November 10, 2016, a tremendous milestone for OSU and the state of Oregon.<\/p>\n

The 800 MHz spectrometer<\/a> is the highest field NMR in the state of Oregon and one of only 50 nationwide. The new instrument will advance research on protein folding, gene discovery and biochemical structural informatics used to treat diseases, such as Alzheimer\u2019s and cancer.\u00a0The OSU NMR Facility<\/a> is a campus-wide core facility dedicated to providing state-of-the-art NMR spectroscopy resources to the research and education community at OSU and throughout the Pacific Northwest.<\/p>\n

Housed in the Linus Pauling Science Center, the NMR Facility houses five NMR spectrometers that are supported by expert staff\u00a0and managed by a full-time director interested in collaborating and supporting users with diverse scientific interests. Biochemistry and Biophysics alumnus Patrick Reardon<\/a> (\u201801) was hired as the Director of the new NMR Facility. Dr. Reardon received his Ph.D. in biochemistry from Duke University, where he focused on NMR spectroscopy and its application to complex biological systems.<\/p>\n

Elisar Barbar<\/a>, professor of biochemistry and biophysics at OSU, chaired the NMR Steering Committee and was the PI on the NIH and Murdock\u00a0grant proposals. She led the three-year collaborative effort with researchers from OSU, University of Oregon, Oregon Health and Science University, Portland State University and Lewis & Clark College. The efforts paid off when the team was awarded more than $2.4 million from the National Institutes of Health, the\u00a0M.J.\u00a0Murdock\u00a0Charitable\u00a0Trust\u00a0and OSU.\u00a0The High End Instrumentation grant received from NIH is one of only two in Oregon awarded during the last 10 years.<\/p>\n

The facility supports scientific inquiry in a diverse array of research areas, such as structural biology, organic chemistry, natural products analysis and environmental studies.\u00a0The instruments include: the 800 MHz, 700 MHz, 500 MHz and 400 MHz (two), corresponding to magnetic field strengths that range from 18.8 T to 9.4 T.\u00a0Data processing and analysis software is available on workstations in the facility.<\/p>\n

The 800 MHz spectrometer will enhance graduate and undergraduate education and career opportunities in the biological sciences at OSU. Students will learn to effectively utilize the equipment to conduct research at the interface of structural and cell biology.<\/p>\n

Guests included the OSU community, scientists from national laboratories, university partners across the region as well as Interim Provost Ron Adams and President Ed Ray.<\/p>\n

Angela Gronenborn presented a keynote address that touched on the history and key benefits of NMR as well as a scientific seminar on “Fluorine NMR- protein folding, structure and drug binding to HIV Reverse Transcriptase.” Gronenborn\u00a0established the Department of Structural Biology at the University of Pittsburgh School of Medicine in 2005 and is currently the department head. She holds the UPMC Rosalind Franklin Chair.<\/p>\n","protected":false},"excerpt":{"rendered":"

The College of Science celebrated the new Macromolecular Nuclear Magnetic Resonance instrument (NMR) with a Dedication Ceremony November 10, 2016.<\/p>\n","protected":false},"author":5667,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-6257","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/p6vHeb-1CV","jetpack-related-posts":[{"id":4939,"url":"https:\/\/dev.blogs.oregonstate.edu\/impact\/2016\/10\/biochemistry-alumnus-direct-nmr-facility\/","url_meta":{"origin":6257,"position":0},"title":"Biochemistry alumnus to direct NMR facility","author":"farrisd","date":"October 5, 2016","format":false,"excerpt":"Biochemistry alumnus Patrick Reardon (\u201801) returns to OSU as Director of the new Nuclear Magnetic Resonance Facility.","rel":"","context":"In "Biochemistry & Biophysics"","block_context":{"text":"Biochemistry & Biophysics","link":"https:\/\/dev.blogs.oregonstate.edu\/impact\/category\/departments\/bb\/"},"img":{"alt_text":"Patrick Reardon ('01), NMR Facility Director","src":"https:\/\/i0.wp.com\/blogs.oregonstate.edu\/impact\/files\/2016\/10\/Patrick-Reardon.png?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":1665,"url":"https:\/\/dev.blogs.oregonstate.edu\/impact\/2015\/06\/high-powered-nuclear-magnetic-resonance-instrument-to-draw-regional-national-and-international-scientists-to-osu\/","url_meta":{"origin":6257,"position":1},"title":"High-powered nuclear magnetic resonance instrument to draw regional, national and international scientists to OSU","author":"nayaks","date":"June 9, 2015","format":false,"excerpt":"Elisar Barbar and her team were recently awarded $1.3 million by the National Institutes of Health (NIH) and another $504,000 from M.J. Murdock Charitable Trust","rel":"","context":"In "Biochemistry & Biophysics"","block_context":{"text":"Biochemistry & Biophysics","link":"https:\/\/dev.blogs.oregonstate.edu\/impact\/category\/departments\/bb\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":7574,"url":"https:\/\/dev.blogs.oregonstate.edu\/impact\/2017\/07\/inaugural-symposium-explores-nmr-illuminates-biology\/","url_meta":{"origin":6257,"position":2},"title":"Inaugural symposium explores how NMR illuminates biology","author":"farrisd","date":"July 12, 2017","format":false,"excerpt":"The College of Science is hosting the inaugural symposium on biological Nuclear Magnetic Resonance featuring internationally recognized NMR scientists on August 4, 2017.","rel":"","context":"In "Biochemistry & Biophysics"","block_context":{"text":"Biochemistry & Biophysics","link":"https:\/\/dev.blogs.oregonstate.edu\/impact\/category\/departments\/bb\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.oregonstate.edu\/impact\/files\/2017\/07\/NMR-Ribbon-Cutting2_web.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":9898,"url":"https:\/\/dev.blogs.oregonstate.edu\/impact\/2018\/07\/intrinsically-disordered-protein-mystery-solved\/","url_meta":{"origin":6257,"position":3},"title":"Intrinsically disordered protein mystery solved","author":"Katharine de Baun","date":"July 31, 2018","format":false,"excerpt":"Biophysicist Elisar Barbar and team have discovered that the intrinsically disordered state of the protein ASCIZ, a key transcription factor within cells, plays a major role in regulating production of the protein LC8.","rel":"","context":"In "Biochemistry & Biophysics"","block_context":{"text":"Biochemistry & Biophysics","link":"https:\/\/dev.blogs.oregonstate.edu\/impact\/category\/departments\/bb\/"},"img":{"alt_text":"Elisar Barbar, Professor of Biochemistry and Biophysics","src":"https:\/\/i0.wp.com\/blogs.oregonstate.edu\/impact\/files\/2018\/07\/Elisar-Barbar.png?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":8981,"url":"https:\/\/dev.blogs.oregonstate.edu\/impact\/2018\/04\/understanding-sciences-highest-awards\/","url_meta":{"origin":6257,"position":4},"title":"Understanding science’s highest award: The Nobel Prizes","author":"nayaks","date":"April 2, 2018","format":false,"excerpt":"Three OSU scientists explore the 2017 Nobel Prizes in physics, chemistry and medicine and the scientific advances they represent at a public lecture.","rel":"","context":"In "Biochemistry & Biophysics"","block_context":{"text":"Biochemistry & Biophysics","link":"https:\/\/dev.blogs.oregonstate.edu\/impact\/category\/departments\/bb\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":9855,"url":"https:\/\/dev.blogs.oregonstate.edu\/impact\/2018\/07\/amber-vogel-selected-as-2018-mathews-fellow-in-biochemistry-to-study-drug-discovery\/","url_meta":{"origin":6257,"position":5},"title":"Amber Vogel selected as 2018 Mathews Fellow in biochemistry to study drug discovery","author":"farrisd","date":"July 19, 2018","format":false,"excerpt":"Ph.D. student Amber Vogel received the 2018-19 Christopher and Catherine Mathews Graduate Fellowship in biochemistry and biophysics.","rel":"","context":"In "Alumni and Friends"","block_context":{"text":"Alumni and Friends","link":"https:\/\/dev.blogs.oregonstate.edu\/impact\/category\/people\/alumni-and-friends\/"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/posts\/6257","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/users\/5667"}],"replies":[{"embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/comments?post=6257"}],"version-history":[{"count":8,"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/posts\/6257\/revisions"}],"predecessor-version":[{"id":6265,"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/posts\/6257\/revisions\/6265"}],"wp:attachment":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/media?parent=6257"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/categories?post=6257"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/impact\/wp-json\/wp\/v2\/tags?post=6257"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}