{"id":23,"date":"2012-05-24T21:25:49","date_gmt":"2012-05-24T21:25:49","guid":{"rendered":"http:\/\/blogs.oregonstate.edu\/halflife\/?p=23"},"modified":"2014-06-06T22:21:36","modified_gmt":"2014-06-06T22:21:36","slug":"andy-karplus-kay-diederichs-article-describing-waste-want-way-improving-protein-structure-determination-appears-may-25th-issue-science","status":"publish","type":"post","link":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/2012\/05\/24\/andy-karplus-kay-diederichs-article-describing-waste-want-way-improving-protein-structure-determination-appears-may-25th-issue-science\/","title":{"rendered":"Andy Karplus and Kay Diederich&#8217;s article describing a &#8220;waste not, want not&#8221; way of improving protein structure determination appears in the May 25th issue of Science"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.oregonstate.edu\/halflife\/files\/2014\/06\/Andy-with-model-caption.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-24 aligncenter\" alt=\"Andy with model caption\" src=\"http:\/\/blogs.oregonstate.edu\/halflife\/files\/2014\/06\/Andy-with-model-caption-300x225.jpg\" width=\"300\" height=\"225\" srcset=\"https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/1935\/files\/2014\/06\/Andy-with-model-caption-300x225.jpg 300w, https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/1935\/files\/2014\/06\/Andy-with-model-caption.jpg 500w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>Andy describes the work as a &#8220;new assessment strategy for X-ray diffraction data that shows that current standards force people to throw away useful data (because they think they are too noisy), and that keeping these additional data will allow every crystal structure to be about 10% more accurate&#8221;. The work was begun during Andy&#8217;s sabbatical with Kay Diederich at the University of Konstanz last year.<\/p>\n<p>The <em>Science<\/em> article, entitled &#8221; Linking crystallographic model and data quality&#8221;, is accompanied by a <em>Perspective<\/em> by Phil Evans, entitled &#8220;Resolving some old problems in protein crystallography&#8221;. Protein crystallographer Dale Tronrud comments that the new method has the &#8220;potential to alter the routine practice of crystallographers around the world and has applications to many fields beyond crystallography&#8221;. For more about the Science article, see Nick Houtman&#8217;s &#8220;X-ray Vision&#8221; piece in OSU&#8217;s <a href=\"http:\/\/oregonstate.edu\/terra\/2012\/05\/x-ray-vision\/\">Terra<\/a>.<\/p>\n<p>Congratulations Andy on &#8220;revealing how life works&#8221;.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Andy describes the work as a &#8220;new assessment strategy for X-ray diffraction data that shows that current standards force people to throw away useful data (because they think they are too noisy), and that keeping these additional data will allow every crystal structure to be about 10% more accurate&#8221;. The work was begun during Andy&#8217;s&hellip; <a href=\"https:\/\/dev.blogs.oregonstate.edu\/halflife\/2012\/05\/24\/andy-karplus-kay-diederichs-article-describing-waste-want-way-improving-protein-structure-determination-appears-may-25th-issue-science\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":5976,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-23","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/posts\/23","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/users\/5976"}],"replies":[{"embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/comments?post=23"}],"version-history":[{"count":2,"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/posts\/23\/revisions"}],"predecessor-version":[{"id":123,"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/posts\/23\/revisions\/123"}],"wp:attachment":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/media?parent=23"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/categories?post=23"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/halflife\/wp-json\/wp\/v2\/tags?post=23"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}