{"id":2610,"date":"2010-07-19T10:00:36","date_gmt":"2010-07-19T18:00:36","guid":{"rendered":"http:\/\/blogs.oregonstate.edu\/collegeofveterinarymedicine\/?p=2610"},"modified":"2010-07-19T13:19:26","modified_gmt":"2010-07-19T21:19:26","slug":"rockey-laboratory-receives-grant-from-siga-technologies-inc","status":"publish","type":"post","link":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/2010\/07\/19\/rockey-laboratory-receives-grant-from-siga-technologies-inc\/","title":{"rendered":"Rockey laboratory receives grant from SIGA Technologies, Inc."},"content":{"rendered":"<div id=\"attachment_2631\" style=\"width: 170px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-2631\" class=\"size-full wp-image-2631 \" title=\"Rockey Dan vg\" src=\"http:\/\/blogs.oregonstate.edu\/collegeofveterinarymedicine\/files\/2010\/07\/Rockey-Dan-vg.jpg\" alt=\"\" width=\"160\" height=\"205\" srcset=\"https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/448\/files\/2010\/07\/Rockey-Dan-vg.jpg 200w, https:\/\/osu-wams-blogs-uploads.s3.amazonaws.com\/blogs.dir\/448\/files\/2010\/07\/Rockey-Dan-vg-117x150.jpg 117w\" sizes=\"auto, (max-width: 160px) 100vw, 160px\" \/><p id=\"caption-attachment-2631\" class=\"wp-caption-text\">Dr. Dan Rockey<\/p><\/div>\n<p><a href=\"http:\/\/oregonstate.edu\/vetmed\/departments\/biomedicalsciences\/microbiology\/faculty\/rockey\">Dr. Dan Rockey<\/a> recently received a 2-year award to work with a local biotechnology company on a broad-spectrum anti-infective compound known as ST-669.\u00a0 SIGA Technologies, Inc. is a company specializing in the development of pharmaceutical agents to fight biowarfare pathogens. The company recently was awarded a multi-million dollar contract from the Department of Defense to support the preclinical development of this compound.\u00a0 ST-669 has shown sub-micromolar in vitro antiviral activity against many different and diverse viral pathogens of humans and animals. Several of these pathogens are serious threats to human health, and thus are designated &#8220;Category A&#8221; and &#8220;Category B&#8221; by the U.S. Centers for Disease Control and Prevention.<\/p>\n<p>Individuals in Dr. Rockey\u2019s laboratory are working with researchers at SIGA to examine the activity of ST-669 against additional pathogens of interest, and to develop an understanding of the mechanism of action of the drug within a host.\u00a0 Dr. Rockey said, \u201cThe specific molecular target of the drug is an important issue because identification of the target will allow investigators to improve the inhibitory activity of ST-669 through minor chemical modification. We also can use this information to perhaps identify additional and novel compounds specific to the target. It is a particularly interesting subject because of the broad specificity of the drug.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Dan Rockey recently received a 2-year award to work with a local biotechnology company on a broad-spectrum anti-infective compound known as ST-669.\u00a0 SIGA Technologies, Inc. is a company specializing in the development of pharmaceutical agents to fight biowarfare pathogens. The company recently was awarded a multi-million dollar contract from the Department of Defense to [&hellip;]<\/p>\n","protected":false},"author":911,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[3054,3051],"tags":[],"class_list":["post-2610","post","type-post","status-publish","format-standard","hentry","category-faculty-and-staff","category-research"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p3DBMX-G6","_links":{"self":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/posts\/2610","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/users\/911"}],"replies":[{"embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/comments?post=2610"}],"version-history":[{"count":14,"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/posts\/2610\/revisions"}],"predecessor-version":[{"id":2742,"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/posts\/2610\/revisions\/2742"}],"wp:attachment":[{"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/media?parent=2610"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/categories?post=2610"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dev.blogs.oregonstate.edu\/collegeofveterinarymedicine\/wp-json\/wp\/v2\/tags?post=2610"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}