Dr. Manoj Pastey, Noah Lawler, Donna Mulrooney, and Andree Hunkapillar.
From the outside, the OSU Veterinary Research Laboratory (VRL) doesn’t look like a high-tech center of advanced disease testing, but behind the drab, cement-block walls, are highly-trained experts and hundreds of thousands of dollars’ worth of state-of-the-art equipment.
There are several teams working in the VRL, which is managed by the Oregon Veterinary Diagnostic Laboratory (OVDL). On the Molecular Diagnostic (MD) team are Section Head Manoj Pastey, Supervisor Donna Mulrooney, and Microbiologists Andree Hunkapiller and Noah Lawler. They use DNA to find the causes of disease in all kinds of critters, from chickens to llamas. “Basically we are looking for specific gene sequences that identify a pathogen – a virus, bacteria or parasite – in a sample,” says Mulrooney. “The sample can be anything from a piece of lung, to fecal samples, to blood,” she says.
Most of the customers for the lab are Oregon veterinarians, many of whom work in the OSU Veterinary Teaching Hospital, but there are also customers from other states. “We have tests that are unique to our lab, so we get samples from across the U.S.,” says Mulrooney. “For instance we have a test for Mycoplasma haemolamae, a blood parasite that can cause severe anemia in alpacas and llamas.” That test was developed right here at the OSU College of Veterinary Medicine by Dr. Susan Tornquist and Dr. Chris Cebra
The molecular diagnostics lab also works with state and federal agencies. They receive weekly samples from Oregon’s state veterinarian for screening of avian influenza. “We test samples from the live bird market in Woodburn,” says Mulrooney. Avian influenza is a serious problem for farmers because it spreads very quickly and is deadly to poultry.
The OVDL is a member of a national surveillance network, under the U.S. Department of Agriculture, that works to respond quickly to disease outbreaks. That means the MD team has to be prepared to take on heavy loads of extra testing on a moment’s notice. “In the event of a multi-state outbreak of something like avian influenza, we have to cancel vacations and work long hours,” says Hunkapiller.
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